FanDuel NFL Week 4 2025 Main Slate Advice
Constructing a winning FanDuel lineup requires a careful balance between elite talent, mid-tier value plays, and matchups that provide paths to upside. For Week 4, this lineup spreads salary across a core of proven superstars, ascending young receivers, and a defense capable of exceeding expectations at a budget price. Let’s dive into each selection and explore why this group has tournament-winning potential.
Quarterback: Patrick Mahomes – $7,800 (vs. BAL)
Patrick Mahomes remains the centerpiece of any DFS roster when he’s underpriced, and at $7,800 he offers tremendous value. His average of 20.75 fantasy points per game reflects his steady production even against difficult opponents. Facing Baltimore is never easy, but Mahomes thrives in high-pressure environments. The Ravens’ defense is strong, but Mahomes’ creativity outside the pocket and ability to generate chunk plays keep him matchup-proof. His ceiling is always multiple touchdowns with 300 yards, making him a safe and explosive tournament option.
Running Back: Saquon Barkley – $8,700 (at TB)
Saquon Barkley is the offensive engine of the Giants. Averaging 13.43 FPPG, his numbers haven’t yet reflected his true ceiling, but his workload and versatility remain undeniable. Against Tampa Bay, Barkley’s ability to contribute in both the running and passing game ensures consistent touches. The Bucs’ defensive front is tough, but Barkley has the type of game-breaking ability to turn one touch into a 50-yard touchdown. Paying up for him locks in a high-usage player with slate-breaking upside.
Running Back: Ashton Jeanty – $6,800 (at LV)
Ashton Jeanty is a sneaky mid-tier option at just $6,800. Averaging 7.73 FPPG, he’s a developing back with growing usage. Against the Raiders, his matchup is intriguing because Las Vegas has struggled to contain explosive plays from running backs. Jeanty may not command the same recognition as elite backs, but his price allows flexibility elsewhere, and his involvement in the red zone offers touchdown potential. He’s the kind of player who doesn’t need a massive stat line to hit value at his salary.
Wide Receiver: Wan’Dale Robinson – $5,800 (vs. LAC)
Wan’Dale Robinson provides strong salary relief at $5,800. With 12.93 FPPG, he’s emerging as one of Daniel Jones’ most reliable targets. The Chargers’ defense has allowed production to slot receivers, and Robinson’s quickness and ability to gain yards after the catch make him a strong candidate to exceed his value. His upside comes from volume—if the Giants fall behind and lean on short passing, Robinson could rack up double-digit targets.
Wide Receiver: Puka Nacua – $9,400 (vs. IND)
Puka Nacua has quickly established himself as one of the premier fantasy receivers. Averaging 21.66 FPPG, he’s producing like a top-five option every week. At $9,400, he’s the most expensive player in this lineup, but he earns that price tag. Facing Indianapolis, Nacua should again be the focal point of the Rams’ passing attack. His combination of target share, route running, and red-zone usage makes him a near lock for double-digit receptions and 100 yards, with multiple touchdown potential. He’s the lineup’s high-priced anchor.
Wide Receiver: Tre Tucker – $6,000 (vs. CHI)
Tre Tucker is a breakout candidate this week. Averaging 18.56 FPPG, he’s already producing well above his $6,000 salary. The matchup against Chicago is favorable, as the Bears’ secondary has struggled against speed receivers. Tucker’s ability to stretch the field adds big-play upside, which is exactly what you want in a tournament setting. He may not command as many targets as Nacua, but his efficiency and knack for splash plays make him a fantastic value.
Tight End: Zach Ertz – $5,000 (at ATL)
At $5,000, Zach Ertz is a low-cost veteran option who provides stability at a volatile position. Averaging 10.26 FPPG, he still has a role as a safety valve in the passing game. Against Atlanta, he should see opportunities in short-yardage and red-zone situations. While he may not deliver massive yardage, a handful of catches and a potential touchdown would easily pay off his salary. Ertz is the type of steady, affordable tight end that helps balance a lineup built around star receivers.
Flex: Emeka Egbuka – $7,000 (at TB)
Emeka Egbuka is one of the most exciting young receivers in football, and at $7,000 he’s a great flex play. Averaging 14.66 FPPG, he’s consistent while still carrying upside in the right matchup. Against Tampa Bay, his speed and precision routes could create problems for a defense that has struggled to contain outside receivers. Egbuka’s presence in the flex spot gives this lineup another high-upside wideout who can produce a slate-breaking performance without the premium price tag of Nacua.
Defense/Special Teams: Tampa Bay Buccaneers – $3,100 (vs. PHI)
Paying down at defense is a common DFS tactic, and the Buccaneers at $3,100 fit the strategy perfectly. Averaging 6.66 FPPG, they’ve been opportunistic with turnovers and sacks. Facing Philadelphia is not ideal, but Tampa Bay’s aggressive pass rush could still create opportunities for big plays. All you need from a low-cost defense is a path to double-digit points, and with their talent up front, the Buccaneers have that potential.
Final Thoughts
This FanDuel Week 4 lineup strikes a perfect balance between star power and value. Patrick Mahomes offers elite quarterback play at a reasonable price, while Barkley and Nacua provide high-end stability with massive ceilings. Robinson, Tucker, and Egbuka round out the receiving corps with strong matchups and breakout potential. Ertz offers cost-efficient stability at tight end, while Jeanty’s mid-tier price creates flexibility for spending up elsewhere. Finally, the Buccaneers defense provides a low-cost way to fill the lineup without sacrificing ceiling.
With a mix of proven stars and emerging playmakers, this roster is designed to compete in tournaments while maintaining the floor necessary for cash games. If Mahomes connects on a few deep shots and Nacua continues his dominance, this lineup has the upside to rise above the pack.